Preklinisch onderzoek

Amsterdam UMC
VUMC, department of Physiology (contact prof.dr. Coen Ottenheijm)

-ASSAY: In vitro muscle contractility assays (m. soleus and extensor digitorum longus); SPECIES: mouse and rat models
-ASSAY: Myofiber contractility assays; SPECIES: patient biopsies, animal models, cell culture
-ASSAY: Sarcomere contractility assays; SPECIES: patient biopsies and animal models
-ASSAY: Cell culture contractility assays (adult myofibers from m. flexor digitorum longus); SPECIES: mouse models
-ASSAY: Super-resolution microscopy to study sarcomere structure; SPECIES: patient biopsies, animal models, cell culture
-ASSAY: Analyses of giant muscle proteins, such as titin and nebulin; SPECIES: patient biopsies, animal models, cell culture
-ASSAY: Respiratory muscle contractility (assays described above), including effects of mechanical ventilation; SPECIES: animal models
-ASSAY: Whole body plethysmography; SPECIES: mouse models
-ASSAY: Basic histology, including H&E, gomori, picrosirius, fiber typing; SPECIES: patient biopsies, animal models

Amsterdam UMC
AMC, Neurology (contact Anneke van der Kooi, Filip Eftimov?)
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